Summary of Qualifications
• Strong editorial, written, and oral communication skills
• Knowledge of MS Office 2007, Adobe CS3, and Endnote.
• Certified in basic science writing and teaching science.
• Proven ability to plan and prioritize multiple tasks.
• Adaptable to new learning environments.
• Proven ability to work effectively with people of various cultural backgrounds.
2008 Ph.D. in Biochemistry, University of Washington, Seattle, WA.
2000 Bachelor of Science, Biochemistry, University of Washington, Seattle, WA.
1995 Associate of Arts, Emphasis on Psychology, Centralia Community College, Centralia, WA.
05/2009 – Present, National Institutes of Health, Baltimore, MD
My current projects focus on the study of DNA repair proteins with links to rare genetic diseases including Fanconi Anemia and Blooms Syndrome. I design and implement multiple simultaneous research projects for the study of protein function through bioinformatic, biophysical and structural techniques. My research complements the genetic analysis performed by the rest of the group as information discovered on the protein level can be immediately tested in vivo.
Additional Duties include maintenance of equipment, radiation safety waste and records, and coordination of equipment and facility repair.
I have completed a course in science writing and the pedagogy of teaching science.
01/2009-03/2009 – University of Washington, Seattle, WA
09/2002-12/2008 – University of Washington, Seattle, WA
Graduate Student/ Research Associate
04/2000-09/2002 – University of Washington, Seattle, WA
My studies at the University of Washington involved structural characterization of the conserved domains in the breast cancer associated protein 1 (BRCA1) and its constitutive partner BARD1.
Additional duties included supervising and mentoring four undergraduate researchers with a focus on practical training and project management, as well as writing institutional (university level) fellowship/training grant applications for personal research funding and assisting with federal grant research proposals for the lab.
Additional research experience available upon request.
09/2010-11/2010, Completion of 9-week education methods course “Scientists Teaching Science,” by Barbara Houtz, Director of Outreach, Eberly College of Science, Pennsylvania State University.
• Effective science teaching pedagogy
• Development of Bloom’s Taxonomy based lesson plan.
• Development of classroom evaluations and exams
• Constructing a syllabus.
03/2004 – 06/2004, Laboratory Practical for Biochemistry Undergraduate Majors, University of Washington, Seattle, WA
Classroom and Laboratory Instructor
• Teaching four classes of approximately twenty students each.
• Lesson plan development.
• Writing and grading quizzes and exams.
• Preparation of teaching materials and required items for the laboratory practical.
• Hold office hours to assist students.
01/2004 – 03/2004, Biochemistry for Undergraduate Majors (Part 2 of 3), University of Washington, Seattle, WA
10/2003 – 12/2003, Biochemistry for Undergraduate Majors (Part 1 of 3). University of Washington, Seattle, WA
• Teaching two classes of 20-30 students.
• Review material taught during lecture.
• Lesson plan development focused to assist in student learning lecture material through solving homework problems, Q&A sessions, and review.
• Develop new lesson plans for 10% of material not covered during lecture.
• Writing exam questions and grading exams and projects.
• Hold office hours to assist students.
12/2008, University of Washington, Department of Biochemistry, Title - “BARD1 has a Tail to Tell, the Crystal Structure of the BARD1 Ankyrin Repeat Domain and its Functional Consequences.”
09/2008, National Institutes of Health, Laboratory of Genetics. Title - “BARD1 has a Tail to Tell, the Crystal Structure of the BARD1 Ankyrin Repeat Domain and its Functional Consequences.”
03/2008, University of Alberta, Edmonton, Heritage Foundation. Title - “BARD1 has a Tail to Tell, the Crystal Structure of the BARD1 Ankyrin Repeat Domain and its Functional Consequences.”
2004-2007, University of Washington, Molecular Biophysics Training Grant, yearly oral presentation discussing current scientific research.
¬09/2008, National Institutes of Health Graduate Research Festival, Bethesda, MD.
¬01/2008, Keystone Symposium, Frontiers in Structural Biology/Genomics, Steamboat Springs, CO.
06/2007, Victoria/Vancouver NMR Conference, Vancouver, Canada.
2004-2007, Department of Biochemistry Annual Retreat, Leavenworth, WA.
Achievements and Honors
2011, Lead Judge for the NIH Graduate Research Symposium, Structural Biology section.
2010, Judge for NIH Graduate Research Symposium, Structural Biology section.
2010, Scientists Teaching Science certificate.
2008, JBC Paper of the Week, Crystal structure of the BARD1 Ankyrin Repeat Domain and its functional consequences.
2008, NIH National Graduate Student Research Festival Award.
2007, Schultz Graduate Travel Fellowship.
2004-2007, Molecular Biophysics Training Grant.
2000, University of Washington, Department of Biochemistry, Distinction in Biochemistry.
2010-Present, National Association of Science Writers (NASW).
2007-Present, American Association for the Advancement of Science (AAAS).
2000-Present, University of Washington Alumni.
Xu, Dongyi et al. Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO Journal; (2010) 29, 3140-3155.
Islam MN, Fox D 3rd, Guo R, Enomoto T, Wang W. (2010). RecQL5 promotes genome stabilization through two parallel mechanisms-Interacting with RNA polymerase II and Acting as a helicase. Mol Cell Biol. May; 30(10):2460-72. (Co-authorship)
Kacherovsky, N., Tachibana, C., Amos, E., Fox, D., 3rd, and Young, E.T. (2008). Promoter binding by the Adr1 transcriptional activator may be regulated by phosphorylation in the DNA-binding region. PLoS ONE 3, e3213.
Fox, D., 3rd, Le Trong, I., Rajagopal, P., Brzovic, P. S., Stenkamp, R. E., and Klevit, R. E. Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences. J Biol Chem. 2008 Jul 25; 283(30), 21179-86.
Iverson HA, Fox D 3rd, Nadler LS, Klevit RE, Nathanson NM. Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal. J Biol Chem. 2005 Jul 1;280(26):24568-75. (Co-authorship)
Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox D 3rd, Fukuda M, Ohta T, Klevit R. Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5646-51.
Recommendations available upon request.